Mild Cognitive Impairment
Exploratory resting state and event related EEG biomarkers for MCI
Alzheimer’s Disease & Mild Cognitive Impairment
Cross-sectional comparisons resting state EEG/fMRI/PET biomarkers for AD & MCI
Parkinson’s Disease and Lewy Body Dementia
Cross-sectional comparisons resting state EEG/fMRI/PET biomarkers for PD
Frontotemporal Dementia
Exploratory resting state EEG biomarkers for FTD behavioral and aphasia variants
Huntington’s Disease
Evaluation of investigational therapy using resting state EEG biomarker
Mood Disorders
Evaluation of investigational therapy using event related EEG biomarker
Collaboration with J&J to develop event related EEG-based biomarkers to assess mood disorders and efficacy of drug interventions.
Tasks included resting state, 3CVT and custom emotional faces task (EIR) task to measure neural responses to happy, sad and neutral stimuli.
Acquired and analyzed data to validate EIR task during a Phase I, first in man interventional clinical trial. Results supported expanded use of EIR in a follow on clinical assess efficacy of an interventional drug.